Hi, I actually take Cymbalta for my depression, but I'm pretty sure my weight gain is all my fault. The thing is that I did ask my physician, and she recommended i DONT use alli. Although the pharmacist said it was ok and that there would be no interaction between the two, my physician said that if alli is preventing absorption in the intestine of certain things that there is no way of knowing if it is also preventing partial medication absorption. Most of these meds need to go through the blood stream to work. I decided to take alli against her advice because I reallllllllllllllllly want to lose weight, and I've noticed an increase in my own depression and symptoms though I cannot directly correlate them with Alli.
My advice to you would be to observe your ups and downs on meds and within a week or two of starting Alli if you or your loved ones can notice a definite change in your behavior (barring any special stress in life) then maybe Alli is preventing your meds from going into your blood stream. I would also do some research on your particular med to see how it goes into the bloodstream. If it is already in your body and functioning before it even hits your intestine, then no worries.
If you'd like to see a happier world become a happier person. Smile and make sure those around you are always smiling.
Start weight: 163 Goal Weight: 125