Carib Girl, I guess most of us are a little sensitive about someone having anything discouraging to say about something we hope will help us in our battle to lose weight. I imagine there are few here who haven't tried a low fat diet and exercise alone, many times, before now. And there are likely few, if any, of us here who have succeeded trying to do it that way for many reasons. What I hope Alli can provide for me is a better chance of sticking to the plan because instead of trying to limit my calories to just 1200, which can be very boring and lead to feelings of being deprived the foods that normal eaters enjoy, I can enjoy a low fat plan with up to 1800 calories per day if I am exercising, and still lose weight. I know that I am likely to stick with this plan longer, and yes, the fear of "treatment effects" is a motivator and a constant reminder to stay on the plan. I really do have great hope that I can lose my extra weight once and for all this time with the help of Alli and the tools this website provides. As for the negativity, I am surrounded by it already. I haven't even told my husband that I am trying yet another diet plan. I know the reaction I will get from him. Most of us are on these boards for support and motivation. I can understand your question if you have never tried to lose weight without success. I imagine the majority of us here have, many times. Good luck to all!