Seems like it just goes thru my body-I try to take it as late as possible at night-any suggestions for this with treatment effects-should I discontinue taking them? 

 Hello. What do you mean by it seems to "go thru your body"? Are you experiencng treatment effects? If so, how much fat are you eating? CoQ10 supplements do not contain fat so they should not affect your risk of treatment effects. How much fish oil do you take? How many fat grams are in the capsules? I would suggest you examine all the fat you are eating - and be sure to keep your fat intake to about 15 grams per meal.

Fish oil supplements would normally contain 1-2 grams of fat per serving at most - depending on your dose. Let us know and we will try to help further.